If you want to create a new Wine Prefix in Linux the following command (from the terminal) will create a 32bit Wine Prefix.
WINEPREFIX="$HOME/.wine-name" WINEARCH=win32 winecfg
Should you require a 64bit Wine Prefix the following will help:
WINEPREFIX="$HOME/.wine-name" winecfg
.wine-name can be the name of the program you’ll be installing, it will also be a “hidden” directory (as it starts with a dot (.) ) – so if you want to create a Wine Prefix for the game Crysis 2 (for example) you could call your Wine Prefix “.wine-crysis2” or a non-hidden directory “wine-crysis2”. You can even specify the path to where you want your Wine Prefix installed to. Instead of saying:
WINEPREFIX="$HOME/.wine-name"
You could decide to have your Wine Prefix installed somewhere else. (For example)
WINEPREFIX="$HOME/Wine/Installed/Prefixes/Games/.wine-name"
$HOME/ is your /home/username/